Abstract: Seven thick-skinned melon materials were used as parents, of which the female unisexual flower autogamous line was the mother, and 6 single-crosses and 30 tri-crosses were formulated by incomplete biallelic hybridization, and the plant growth characteristics and fruit traits of 43 test materials were measured, and their super-parental and super-neutral dominance were studied, with a view to exploring the comparative hybrid dominance of the single-cross and tri-cross of melons formulated by the use of the female unisexual flower autogamous line.The results showed that the strong dominant combinations were No.12（M123×M112） and No.25（（M123×M113）×M141）.The main traits of the single-cross hybrid had an obvious heterozygous advantage, and the tri-cross hybrid had a heterozygous advantage, but the advantage was not significant, and the variability of the two was not very different.