Abstract: Two kinds of L.barbarum in Ningxia was used as test materials, the effect of lithium on seed germination and seedling growth of Lycium barbarum was studied by using the petri dish method.The critical value and limit value of lithium tolerance concentration in seed germination of L.barbarum materials were established, in order to provide reference for the early breeding of salt tolerant varieties of L.barbarum.The results showed that the germination rate, germination index and length of L.barbarum seeds decreased with the increase of LiCl, and the salt tolerance of different L.barbarum varieties was different.Compared with the control, only the germination rate, germination index and length of ‘Ningqi No.5’ and ‘Ningnongqi No.9’ decreased significantly, but promoted the increase of embryo length of ‘Ningqi No.5’ and ‘Ningnongqi No.9’.When treated with 50 mmol·L^-1 LiCl, the bud length of ‘Ningqi No.5’ did not decrease significantly, but that of ‘Ningnongqi No.9’ did not significantly increase.Compared with the control, when the concentration was 25 mmol·L^-1,its bud length increased significantly, indicating that 25 mmol·L^-1 LiCl promoted the growth of ‘Ningqi No.5’ and ‘Ningnongqi No.9’.Compared with the control, when the concentration was 25 mmol·L^-1,the root was poisoned.The results indicated that the root was less poisoned than the bud the root was less poisoned than the bud.Through the simulated regression curve, it was analyzed that the critical value and limit value of salt in the germination period of ‘Ningqi No.5’ and ‘Ningnongqi No.9’ were 115.10 mmol·L^-1 and 265.61 mmol·L^-1,97.12 mmol·L^-1 and 257.58 mmol·L^-1.The order of inhibition degree of different concentrations of lithium on seed germination characteristics and young seedlings growth of the two varieties was as follow, ‘Ningnongqi No.9’＜‘Ningqi No.5’.Therefore, only ‘Ningqi No.5’ and ‘Ningnongqi No.9’ were suitable for repairing saline soil with low lithium content.