Abstract: ‘Hongzhu No.3’ was hybridized with ‘Hongzhu’,red asparagus lettuce with green stem and strong disease resistance as female parent, and QH13-9,late-maturing green asparagus lettuce with bolting resistance as male parent.Using systematic breeding method, the new variety of early-maturing and bolting resistant red asparagus lettuce was selected after 6 generations of directional breeding.It takes about 75 days from transplant to harvest in cool area of Gansu Province.Red oval-shaped wrinkled leaf, plant height is 53.4 cm, long stick jade green stem with diameter is about 4 cm, rich in iron, potassium, zinc and other trace elements.It is strong resistance to disease.The average single plant weight is around 0.75 kg, the average yield is more than 4 500 kg per 667 m~2.It is suitable for planting in cold areas of Gansu Province and the same climate areas.