Abstract: Lycium barbarum L. is a commonly used bulk medicinal material and a medicinal material with the same origin as medicine and food, and the demand is increasing year by year.It is extremely vulnerable to pests and diseases in the growth process, and pesticide farmers mainly use chemical pesticides for control, so the problem of pesticide residues has also attracted much attention.This study reviewed the characteristics of common pesticide residues in wolfberry from 2000 to 2021,the detection methods of pesticide residues and the status quo of pesticide residues exceeding the standard, and compared the limit standards of pesticide residues in wolfberry at home and abroad, in order to provide reference for the scientific use of wolfberry, standardized production and quality control of medicinal materials, and to promote the international development of the wolfberry industry.At present, the content of pesticide residues in wolfberry is at a low level as a whole, but there are still excessive residues of carbendazim and pyrethroids.The detection methods of pesticide residues are also constantly updated with the changes in the types of pesticide residues.Now the most commonly used detection methods.It is a gas chromatography-mass spectrometry technique; no reports of health risks caused by pesticide residues in wolfberry have been found at home and abroad.Pesticide residues are an important factor restricting the international development of wolfberry.In production, the development of biological control methods has been increased and the ecological planting technology of wolfberry has been established.