Abstract: Taking traditional Chinese medicine residue organic fertilizer as the research object and using Meta-analysis method, a total of 32 articles were selected, included 388 relatively independent data sets.The comprehensive effects of traditional Chinese medicine residue organic fertilizer on crop growth and development, soil chemical properties and enzyme activity were studied, in order to provide reference for the rational utilization of traditional Chinese medicine residue resources and green and low-carbon development in China.The results showed that the application of traditional Chinese medicine residue organic fertilizer significantly increased the crop yield, chlorophyll content and soil pH,soil sucrase and catalase activity, increased by 15.30%,25.90%,14.50%,40.70% and 14.80%,respectively, over no fertilizer application.The total plant biomass showed a gradual increase with the prolongation of traditional Chinese medicine residues（P＜0.01）,and the effect value of soil urease showed a trend of increasing and then decreasing with the prolongation of fertilizer application.The positive effect of traditional Chinese medicine residues on soil properties of medicinal plants was better than that of agricultural crops and vegetables.In conclusion, the rational application of organic fertilizer with traditional Chinese medicine residues could significantly promote plant growth and development and soil physicochemical properties.