Abstract: ‘Hangjiao 12’ were used as test materials, changes of soil pH and nutrient content, fertilizer requirement law, nutrient absorption of soil and plants were studied, and the effects of coupling of water and fertilizer on plant nutrient, in order to change the traditional production mode of long-season cultivated pepper.The results showed that the content of available potassium decreased significantly by 226.00 mg·kg^-1（P＜0.05）,and the content of available phosphorus increased significantly by 11.95 mg·kg^-1 and then decreased significantly by 15.18 mg·kg^-1（P＜0.05） of soil with pepper growth.The contents of N and P were fruit＞leaf＞stem＞root, K content was leaf＞fruit＞stem＞root, Ca content was leaf＞root＞fruit＞stem at full harvest stage.The K content in leaves and roots increased significantly by 3.95 g·kg^-1 and 2.69 g·kg^-1（P＜0.05） in the coupling of water and fertilize produced area, compared with traditional cultivation.Nitrogen, phosphorus and potassium fertilizer should be applied before harvest, and calcium fertilizer should be applied before full harvest.The K content in leaves and roots increased significantly in the coupling of water and fertilize produced area, compared with traditional cultivation.