Abstract: Saxifraga stolonifera Curt.was used as experimental material, potted plant control experiments methed was used, two CO₂ concentrations of 400 μmol·mol^-1 and 800 μmol·mol^-1 were set, and two water gradients were set for each CO₂ concentration treatment, included normal water content（90% field water content） and drought treatment（40% field water content）.The effects of elevated CO₂ concentration and drought on the growth and medicinal ingredients of Saxifraga stolonifera Curt were studied, in order to provide reference for the cultivation and cultivation of Saxifraga stolonifera Curt.under the background of global climate change.The results showed that the plant height, leaf number, roots, stems, leaves and total biomass of S.stolonifera decreased significantly after drought treatment.The biological yields of secondary metabolites bergenin and gallic acid decreased significantly, while MDA,SOD,and soluble sugar, bergenin and gallic acid content increased significantly.Elevated CO₂ concentration significantly increases the plant height, leaf number, biomass, bergenin and gallic acid content and biological yield of S.stolonifera,and significantly reduces MDA content.Under drought treatment, increased CO₂ concentration significantly increased plant height, leaf number, biomass, soluble sugar, bergenin, gallic acid contents and SOD activity of S.stolonifera,and significantly reduced the MDA content.In conclusion, drought had a significant inhibitory effect on the growth of S.stolonifera.Increasing CO₂ concentration could promote the growth of S.stolonifera,alleviate the negative effects caused by drought, and increase the content of bergenin and gallic acid and biological yield.