Abstract: Taking five kinds of nematicidal agents and ‘Zhangji’strawberry as test materials,the control effects of five kinds of nematicidal agents on southern root-knot nematode of strawberry in greenhouse were studied by indoor toxicity test and field depression efficacy test,in order to provide scientific basis for safe nematicides in strawberry production.The results showed that the toxicity of tested nematicides against Meloidogyne incognita from high to low was as follows,41.7%fluopyram＞35% sistan＞20% allyl isothiocyanate＞10% avermectin·fosthiazate＞5% avermectin after 24 hours of treatment,with the LC50 value were 1.389 1,11.546 6,15.602 5,41.978 7,85.347 8 mg·L-1,respectively.Field trials showed that the tested nematicides of fluopyram 41.7%SC,sistan 35% AS,and allyl isothiocyanate 20% EW against M.incognita got excellent control efficacy at the tested concentration,and field control efficacy increased by adding the organosilicon auxiliary of Ruixiaojia.All tested nematicides in field trials were safe for the treated host plants.Fluopyram,sistan,and allyl isothiocyanate were recommended to be applied in M.incognita control practice because of their high toxicity and excellent field efficacy against M.incognita.