Abstract: Taking Codonopsis tangshen seeds as test materials,field experiments were conducted to study the control effects of organic matter（OM）,quicklime（QL）and calcium magnesium phosphate fertilizer（CMP）on the continuous cropping obstacles of C.tangshen,in order to provide reference for reducing continuous cropping obstacles of C.tangshenthrough soil improvement.The results showed that,1)the yield of C.tangshen under the OM,QL and CMP treatments were improved by 37.9%,77.9%,117.4%,respectively,compared with the control.2) OM,QL and CMP treatments significantly increased the total chlorophyll and carotenoid content by 31.6%,18.2%,25.3%and28.7%,18.0%,24.0%,respectively.3) The CAT activities in OM and QL treatments were significantly increased,while the ■content was dramatically decreased.4)The flavonoid content in the QL and CMP treatments was increased by 31.5%and 17.6%,respectively.Furthermore,OM treatment significantly increased the alkaloid content by 58.7%.5) QL and CMP treatments incereased the soil pH and alkaline phosphatase activity by 10.9%,9.8%and 95.4%,69.1%,respectively.Moreover,OM,QL and CMP treatments dramatically incereased the catalase activity by16.7%、21.0%and 20.1%,respectively.6)All the three soil amendments promoted the morphological development,yield and photosynthetic pigment accumulation of C.tangshen.The promotion effects on the growth of C.tangshenfollowed the order of QL （CE=1.31）＞CMP （CE=1.11）＞OM （CE=1.02）.In conclusion,the soil amendments can effectively alleviate the continuous cropping stress of C.tangshen mainly by regulating photosynthetic metabolism,antioxidation,and soil enzyme activity.The comprehensive analysis showed that the promotion effects of the three amendments on C.tangshen growth followed the order of QL (3 000kg·hm^-2)＞CPM (3 000kg·hm^-2)＞OM (4 500kg·hm^-2).