Abstract: In order to explore the influences of different pretreatments and detection methods on the determination results of lead contents in starch and its products, the starch and starch products were selected as samples and treated by wet digestion and microwave digestion, then the lead contents were determined by graphite furnace atomic absorption spectrometry（GFAAS）, inductively coupled plasma mass spectrometry（ICP-MS） and flame atomic absorption spectrometry（FAAS） in national standard, and the application values of different pretreatments and detection methods were evaluated from the recovery rates, precision and economy of the methods. The results showed that the recovery rates of two pretreatments were better, and the precision of microwave digestion was higher than that of wet digestion. The lead contents determined by ICP-MS was significantly higher than that by GFAAS（P＜0.05）, and the precision and recovery rate of ICP-MS were better than that of GFAAS, and the lead contents in samples were lower than the detection limit of FAAS, so it could not be determined. The lead contents in all kinds of starch products were generally higher than that in starch. Except FFAS, the two detection methods and the two pretreatment methods all met the detection requirements of this kind of samples, and the best pretreatment and detection methods could be selected according to precision requirements and laboratory conditions.