Abstract: Molecular dynamics（MD） technology can be used to explore the properties of films made by mixing protein and starch. MD explains the conformation of atoms and molecules at the microscopic level that cannot be observed with the naked eye, and can provide information such as the hydrogen bond force, electrostatic force, van der Waals force,Coulomb force, and chemical bond energy between protein and starch at a certain state, which is helpful for researchers to understand or develop new materials. This review focused on protein-starch edible films, microwave heating（MH）, MD principle and applications, and analyzed the research status and correlation between protein, starch and protein-starch films and microwave heating. MD technology further reveals the microstructure changes and mechanism of protein-starch based materials under MH environment, which can provide reference for the development and utilization of protein-starch based films.