Abstract: Vitamin A（VA） is the indispensable substance and the most easily deficient fat-soluble compound for human body. This paper introduces the physiological function of vitamin A and vitamin A deficiency（VAD）, and reviews the effects of vitamin A with intestinal barrier, intestinal infectious diseases and autism spectrum disorder（ASD） on childrenphysiological function, in order to provide new ideas for studying the function of vitamin A in organism related diseases.