Abstract: Zizyphus jujube, one of the main dried fruits in Xinjiang, is an important source of dietary polysaccharides. In order to optimize the extraction conditions of jujube polysaccharides, with Zizyphus jujube from Xinjiang as the raw materials, the influence of material-liquid ratio, ultrasonic time, water bath temperature and water bath time on the yield of jujube polysaccharide were analyzed through single factors experiments, and the response surface optimization test was conducted using polysaccharide yield as the response value. The results showed that the best extraction conditions of jujube polysaccharides were as follows: the material-liquid ratio 1∶30（g/mL）, ultrasonic time 20 min, water bath temperature 70 ℃ and water bath time 3 h, the yield of jujube polysaccharide was 3.12%.Which lay the foundation for the further utilization of Zizyphus jujube resources to develop healthy products.