Abstract: The ground test of spacecraft needs simultaneous sampling of two channels and wireless data transmission. This paper presents a two-parameter synchronous acquisition and wireless transmission system for spacecraft ground tests. The design uses FPGA to produce a device with simultaneous sampling of two channels. The wireless transmission mode has long-distance LoRa and high-speed GFSK modulation mode, realizing synchronous real-time wireless transmission of acceleration and pressure parameters. Flash storage mode is designed to read data through wired communication when wireless transmission may fail. The signal source frequency is within 2 kHz, which realizes dual channel synchronous acquisition and waveform reproduction of transmitted data. The GFSK wireless transmission rate is up to 2 Mbit/s and the transmission distance is 0.5 km. At the LoRa wireless transmission rate of 1 kbit/s, the long-distance wireless transmission of 1.2 km can be realized. The system realizes the synchronous, long-distance and real-time acquisition and monitoring of two parameters in an overload environment.