Abstract: Taking the T-V1165 S vertical machining center of an enterprise as the research object,the finite element model of the machine tool is established by ANSYS. The natural frequency of the machine tool is simulated,and the dynamic performance of the machine tool is analyzed. At the same time,the harmonic response of the modified finite element model is analyzed to determine the key parts of the machine tool,which provides an important basis and direction for the subsequent secondary design and optimization of the machine tool.