Abstract:
The increasing incidence of allergic diseases caused by plant allergens such as pollens has become both a global public health problem and an environmental and health risk worrying more and more governments all over the world. The animal model for pollen allergy is the key link of studying the occurrence and allergic mechanism of plant allergic diseases, which could not only provide important references for the clarification of mechanism of pollen allergy and related research, but also effectively and accurately evaluate and detect pollen allergens and promote prevention strategies of plant allergic diseases as like pollinosis. This paper summarized the research data of animal models of pollen allergy about strain types, model construction methods, breeding strategies, test and evaluation methods, and the advantages, disadvantages and application of animal models of pollen allergy in recent years to provide reference for the establishment of appropriate experimental animal models of pollen allergy and related basic and applied research.