Abstract: Biostatistics with experimental design, a course of combination of theories and applications with strong practicality, involves sections of instruments, methodology and experimental techniques. This paper expounded the characteristics of the course of biostatistics with experimental design and the significance of integrating ideological and political education, and put forward an effective way for integration. The ideological and political elements could be integrated into teaching process by introduction of classical cases and clarification of basic concepts and principles, with the aiming to strengthen ideological and political accomplishments of college students, improve class-teaching efficiency and demonstrate the educational function of the course.