Abstract: In order to promote the control of watermelon leaf blight in the field,13 fungicides were used to inhibit the growth rate of mycelium.The results showed that different fungicides had different inhibitory effects on watermelon leaf blight.The inhibition rates of 50%iprodione WP 1 000 times and 50% prochloraz manganese salt WP 1 500 times were 97.15%and 96.67%,respectively.The inhibition rates of 64%oxadiazole·mancozeb WP 500 times,250 g·L^-1 pyraclostrobin EC 1 500 times,25% prochloraz EC 1 000 times,80%azoxystrobin WG 2 000 times and 25% bromconitrile WP 1 000 times were 93.95%,93.11%,92.74%,92.34% and92.27%,respectively.Seven kinds of low toxic fungicides were selected to control watermelon leaf blight,which could be used alternately in production.