Abstract: In order to observe the effects of different formulas of new fertilizer and conventional fertilizer on the growth and yield of pepper, three new fertilizers of Dikangbao microbial fertilizer, organic silicon calcium magnesium fertilizer and blue sea peninsula soil conditioner were selected, and nine fertilizer formulations were designed for experiment. The results showed that with the increase of organic fertilizer and the decrease of compound fertilizer, the yield increased first and then decreased, and reached the peak at T2 application of organic fertilizer 2 000 kg·（667 m~2）^-1 + compound fertilizer 40 kg·（667 m~2）^-1, which was 30.77% higher than that of the control, and the yield increased by 25.25%, but the fertilizer utilization rate（PFP） began to decrease. Compared with the control, the new fertilizer treatment increased the dry matter content of the underground part. Among them, T6 application of organic fertilizer 1 500 kg·（667 m~2）^-1+compound fertilizer 60 kg·（667 m~2）^-1+ organic silicon calcium magnesium fertilizer 60 kg·（667 m~2）^-1 had a significant yield-increasing effect. The yield and PFP were 43.81% and 38.61% higher than the control, respectively, and 20.59% lower than the total fertilizer application rate of T2, with an increase of 14.82% and PFP increased by 44.76%. Dikangbao microbial fertilizer in T5 improved PFP, but the difference was not significant between the treatments; Through different formula tests, it was also found that the fertilizer efficiency of the selected three new fertilizers were not stable enough.