Abstract: In order to promote the promotion and application of high resistance sesame varieties, this article introduced the breeding process, characteristic characteristics, yield performance, and cultivation techniques of Wanzhi 19. Wanzhi 19 was a new sesame variety developed by the Nanyang Academy of Sciences, used Wan 9013-2 as the female parent and Zhongzhi 7 as the male parent. It had been bred through sexual hybridization, multiple disease nursery evaluations, and higher generation evaluations. Participated in regional trials in the Huanghuai Region from 2018 to 2019, with an average yield of 95.45 kg·（667 m~2）^-1 over the past two years, an increase of 10.31% compared to the control Yuzhi 4. In April 2021, it passed the Crop Variety identification in Henan Province and was registered as Yupinjian Sesame 2021011. The plant height of Wanzhi 19 is 189.3 cm, the first capsule height is 74.9 cm, the empty tip is 4.7 cm, the main stem and fruit axis length is 109.7 cm, the number of capsules per plant is 95.1, the number of capsules per capsule is 59.2, and the 1000-grain weight is 3.073 g. Good yield potential, good adaptability and stability, stain tolerance, drought tolerance, disease resistance, summer sowing period is 87 days, suitable for planting in Huanghuai Region.