Abstract: Genetics is one of the basic compulsory courses for undergraduate students majoring in agriculture, which is highly confluent and intersected with others crop genetics and breeding courses.The purpose of genetics course construction is to promote the construction and development of genetics curriculum of agricultural specialty in characteristic applied universities and improve teaching quality and students′ professional quality.In this study, the teaching situation and existing problems of genetics course were analyzed, then discussed the direction of genetics course construction from the aspects of knowledge system optimization, teaching strategy renewal, ideological and political education reform and personalized teaching exploration.We put forward some specific reform measures for genetics curriculum construction, including optimizing knowledge system, updating teaching strategies, exploring personalized teaching, optimizing evaluation indexes, digging deep into ideological and political factors.The above reform measures have been put into practice in the genetic teaching of college students majoring in plant production in class 2020.The analysis results of final grades showed that the proportion of students more than 60,75-90 and more than 90 scores were 92.24%,33.59% and 26.87%,respectively.Comparted with the 2019 class, the increase rate were 10.61%,8.11%,and 7.14%,respectively.