Abstract: In order to improve the production quality of Scutellaria baicalensis Georgi in Liupan Mountain Area of Ningxia, taking two-year-old Scutellaria baicalensis Georgi as the research object, the "3414" complete test scheme, namely the field test of three factors, four levels and 14 treatments of nitrogen, phosphorus and potassium, was used to explore the effects of different fertilization rates of nitrogen, phosphorus and potassium on the yield of Scutellaria baicalensis Georgi, and the frequency analysis method was used to calculate the recommended fertilization rate of fertilization.The results showed that the order of the effects of nitrogen, phosphorus and potassium on the yield of Scutellaria baicalensis Georgi was potassium fertilizer＞nitrogen fertilizer＞phosphorus fertilizer.Through frequency analysis, the yield of Scutellaria baicalensis Georgi under optimized fertilization was 7 141.66 kg·hm^-2,the recommended fertilization of nitrogen fertilizer was 96.90-141.99 kg·hm^-2,the recommended fertilization of phosphorus fertilizer was 72.73-101.72 kg·hm^-2,the recommended fertilization of potassium fertilizer was 104.48-151.07 kg·hm^-2,and the fertilization ratio was 1∶0.72-0.75∶1.06-1.08.The recommended amount of fertilizer is more in line with the actual production, and the fertilizer allocation is more reasonable, which is in line with the nutrient demand law of Scutellaria baicalensis.