Abstract: Orobanche aegyptiaca and Orobanche cernua var.cumana cause serious harm to the processing tomato, sunflower, watermelon, muskmelon and other main economic crops in Xinjiang.Methanol extracts of Houttuynia cordata leaves from Guangxi and Sichuan were used as experimental materials, to evaluated induction effect of seed germination of O.aegyptiaca and O.cernua var.cumana and to lay a foundation for the chemical synthesis of “suicide germination” substances.The results showed that the stimulating effect of methanol extract of H.cordata on the germination of seeds was "low promoting and high inhibiting".When the concentration of methanol extract of H.cordata from Sichuan was 8.925 μg·mL^-1,the germination rate of seeds of O.aegyptiaca and O.cernua var.cumana were the highest, 89.18% and 77.57%,respectively.When the concentration of methanol extract of H.cordata from Guangxi was 3 570.000 μg·mL^-1,the germination rate of O.aegyptiaca seeds was the highest, which was 65.38%;At the concentration 0.450 μg·mL^-1,the germination rate of O.cernua var.cumana seeds was the highest, which was 85.39%.In conclusion, H.cordata can be used as a trapping plant to induce suicide germination of O.aegyptiaca and O.cernua var.cumana seeds.