Abstract: In order to screen the srybean field hericides with better cotrol effect suitable for soybean production in Helongjiang Province, in this experiment, eight chemical treatments were set up to investigate the control effect of weed number 20 and 30 days after application, and the control effect of weed fresh weight 45 days after application.The control effect of 83% propargyl fluoride ·acetochlor ·acetochlor EC on annual weeds in soybean field and the effect of chemical treatment on yield were discussed.The results showed that 83% flumioxazin·metribuzin·acetochlor EC had a good control effect on annual weeds in soybean field.Under medium and high dose treatment, the control effect of fresh weight of Polygonum bungeanum Turcz.,Amaranthus retroflexus L.and Echinochloa crusgalli（L.） Beauv, was 97.80%,98.64% and 98.13%,respectively. And the lasting time was about 45 days, and it was safe for soybean.It is suggested that the suitable application period of compound agents in this study is after soybean sowing and before seedling, soil treatment and one-time application.