Abstract: In order to clarify the physico-chemical properties of the tobacco growing soil and their relationships with tobacco leaf quality in Yuxi Tobacco Growing Area, researches on the soil physico-chemical properties of the area were conducted and their correlations with the middle-part leaf appearance quality, the physical characteristics, the chemical components and the sensory evaluation quality were analyzed by using the methods of descriptive statistics and simple correlation analysis. The results showed that: Most of the tobacco-growing soil in Yuxi Tabocco Growing Area was faintly acid and suitable. The contents of organic matter and available nitrogen were rich, available phosphorus was lacked, CEC and available potassium were moderate, and the carbon and nitrogen were relatively small. The soil texture mainly included light loam and medium loam, and the soil bulk density was relatively appropriate. The soil factors significantly related to the appearance quality of freshly flue-cured tobacco leaves were available potassium, organic matter and pH. The soil factors significantly related to the physical characteristics were available potassium, CEC, total phosphorus, total potassium and the carbon nitrogen ratio. The soil factors significantly related to the chemical components of the tobacco leaves are the contents of organic matter, pH, total potassium, total phosphorus and available phosphorus. The soil factors significantly related to the sensory evaluation quality are available nitrogen, available potassium and total potassium. Other soil indexes had little correlation with tobacco leaf quality. The available K promoted the appearance and physical characteristics of flu-cured tobacco leaves, and improved the sensory evaluation scores of cigerettes. The total K improved the chemical ingredient of flu-cured tobacco leaves and thus benefits the sensory evaluation scores of cigerettes. The available N and soil clay contents showed negetive correlation with the sensory evaluation scores of cigerettes.