Research Progress on Transcriptome Sequencing Technology in Coat Color Genetics

For hair use animals, hair color is one of the important economic traits. Hair color is mainly determined by the distribution, proportion and production rate of eummelanin and brown melanin produced by melanocytes. The process of melanin production is regulated by some transcription factors, hormones and signaling pathway molecules. Given the complexity of hair color regulation, the molecular network revealing the regulation of the transcription and regulation of all the genes related with coat color has become increasingly extensive. This paper summarized the research progress of transcriptome sequencing technology in the main fur animals, providing reference data for further screening of hair color regulating genes, and also providing scientific basis for the directional cultivation of fur animals.