Abstract: In order to evaluate the effect of Chinese herbal compund extracts on rabbit intestinal coccidiosis, in this experiment 60 New Zealand white rabbits with mild intestinal coccidiosis infection were randomly divided into six groups, namely the infection without medication group, the high-dose Chinese herbal group, the medium-dose Chinese herbal group, the low-dose Chinese herbal group, the diclazuril group and the chloroguanide group, which were all artificially inoculated with 1×10~5 sporulated oocysts（Eimeria magna,Eimeria media,Eimeria flavescens and Eimeria exigua）. On the 3 rd day after inoculation, the first four groups were administrated via the gastrointestinal tract respectively with 8 mL of physiological saline, 1,0.5,0.2 g/mL Chinese herbal extracts every day; the diclazuril group were given drinking water added 0.3 mL/L diclazuril solution of 5% every day; the chloroguanide group were fed with diet added 600 mg/kg chloroguanide every day. The medication was for seven days, and then stopped. The clinical symptoms of rabbits were observed and recorded every day; all rabbit feces were collected at an interval of seven days, and the number of oocysts per gram of feces（OPG） were detected; the weight gain and death of each rabbit were recorded, the survival rate was calculated, and an autopsy on the dead rabbits was performed. The results showed that the survival rates of rabbits were the same 100% in high-dose Chinese herbal group, the diclazuril group and the chloroguanide group; there was no significant difference in OPG between the three groups of rabbits on the 7 th, 14 th, and 21 th day post-treatment（P＞0.05）. There was no significant difference in rabbit weight gains between the high-dose Chinese herbal group and the chloroguanide group（P＞0.05）. The average weight gain in the diclazuril group during the trial period was significantly higher than those in chloroguanide group and high-dose Chinese herbal group（P＜0.05）. The survival rate of rabbits in medium-dose Chinese herbal group was 90%;its OPG had no significant difference compared with those in chloroguanide group, diclazuril group, high-dose Chinese herbal group（P＞0.05）;and its average weight gain was significantly lower than that in the diclazuril group. The survival rate of rabbits in low-dose Chinese herbal group was 70%;its OPG and weight gain were all significantly lower than those in other treatment groups on the 14 th, and 21 th day post-treatment（P＜0.05）. The results suggested that there was a dose-effect relationship in the treatment of Chinese herbal compound medicine on rabbit intestinal coccidiosis, and the higher dose treatment had the better effect.