Abstract: In order to investigate the effects of adding red ginseng extract in diet on growth performance, nutrient digestion ability, immune ability and antioxidant ability of Alopex lagopus, twenty-four healthy male blue foxes aged about（100±5） days with similar body weight were randomly divided into 4 groups with 6 replicates in each group and 1 blue fox in each replicate, namely control group, experimental low-dose group, experimental medium-dose group and experimental high-dose group. The control group was fed a basal diet, and the low, medium and high dose groups were fed the basal diet containing 1, 2, 4 mL red ginseng extract（the concentration was 80 mg/mL）, respectively. The pretrial period lasted for 7 days, and the trial period lasted for 20 days. Feed, feces and serum samples of each group were collected. Growth performance indexes（initial body weight, final body weight, weight gain, average daily gain and feed/gain）, nutrient（try matter, crude protein, crude fat, organic matter, calcium and phosphorus）apparent digestibility, serum immune indexes（interleukin 2 IL-2, interleukin 4 IL-4, interleukin 6 IL-6, immunoglobulin M IgM, immunoglobulin A IgA, Immunoglobulin G IgG content） and antioxidant indexes（glutathione GSH, nitric oxide NO content and catalaseCAT, superoxide dismutase SOD vitality）, were detected. The results showed that there was no significant difference in initial body weight among all groups（P＞0.05）. The final body weight, the weight gain and average daily gain of experimental groups were significantly higher than those of control group（P＜0.05）. There was no significant difference in average daily feed intake among all groups（P＞0.05）,and the feed/gain of experimental groups was significantly lower than that of control group（P＜0.05）. The final body weight, weight gain and average daily gain were the highest in the high-dose group, and the ratio of feed to gain was the lowest. There were no significant differences in the apparent digestibility of dry matter, crude protein and ether extract among all groups（P＞0.05）. The apparent digestibility of organic matter and calcium in the high-dose group were significantly higher than those in the control group and the low-dose group（P＜0.05）, but there was no significant difference between the high-dose group and the mid-dose group（P＞0.05）. The apparent digestibility of phosphorus in experimental groups was significantly higher than that in control group（P＜0.05）, but there was no significant difference among experimental groups（P＜0.05）.The IL-2 content in medium-dose and high-dose groups was significantly higher than that in control group and low-dose group（P＜0.05）, the IL-6 and IgA contents in high-dose group were significantly higher than that in control group（P＜0.05） and the IgG content in experimental groups was significantly higher than that in control group（P＜0.05）. There was no significant difference in IL-4 and IgM contents among all groups（P＞0.05）. The contents of IL-2, IL-6 and IgA were the highest in the high-dose group. The GSH content, SOD activity and CAT activity of experimental groups were significantly higher than those of control group（P＜0.05）, and the NO content of high-dose group was significantly higher than that of control group（P＜0.05）, among which the GSH content, NO content and CAT activity of high-dose group were the highest. The results indicated that adding red ginseng extract in the diet could improve the growth performance, immune capacity and antioxidant capacity of Alopex lagopus, and improve the nutrient digestion capacity of Alopex lagopus to a certain extent. Within the conditions of this study, adding 4 mL red ginseng extract（the concentration was 80 mg/mL）to the diet of Alopex lagopus had the best effect.