Abstract: (Vibrio mimicus, V.mimicus) is an important pathogen of human and aquatic animals. It can not only cause ulcer disease and ascites disease in aquatic animals, but also cause diarrhea and otitis media in humans, which threatens public health safety seriously. In order to provide reference for effective prevention and control of V.mimicus, this paper reviewed the etiology, clinical characteristics, epidemic status at home and abroad, diagnosis and detection technology, pathogenic mechanism, and prevention and control technology of vibrio mimicry.