Abstract: To improve the enthusiasm of breeding subjects and realize regional collaborative control of pig farming pollution, based on the data of pig manure, urine, chemical oxygen demand, total nitrogen, total phosphorus, copper and zinc production at the provincial level except Taiwan Province, Hong Kong and Macao adminstrative regions in China from 2010 to 2020, this study used the production and emission coefficient method and the environmental cost method to measure the value of environmental pollution generated by pig farming in each region, and proposed a cross-regional compensation mechanism for pig breeding pollution in China. The results showed that from 2011 to 2020, the national（except Taiwan Province, Hong Kong and Macao adminstrative regions） pig breeding industry produced a large amount of pollution, with an average annual output of 199 million t of manure and 302 million t of urine. There were significant differences in the amount of pollution among different regions. Among them, the pollution of manure and urine in Sichuan Province, Hunan Province and Henan Province was more serious, and the chemical oxygen demand was higher than the average level; the total nitrogen production in Hunan Province was the highest, reaching 397 800 t. The regions with the highest total phosphorus production were concentrated in Hunan Province, Henan Province and Sichuan Province, and the production of copper and zinc in Sichuan Province, Shandong Province, Hunan Province, Henan Province and Hebei Province was at a high level. Based on the theory of environmental justice, the compensation amount was calculated the pollution discharge coefficient method and the environmental cost method, and the cross-regional compensation mechanism of pig breeding pollution in China was constructed. The compensation mechanism was divided into prerequisite, implementation mechanism and coordination mechanism, which conforms to the realistic logic of China’s animal husbandry development and was conducive to alleviating the contradiction of pig breeding pollution in the practice of environmental governance.