Abstract: The traditional model sets the driver response time as fixed value, and the driver difference is ignored, which can lead to the error of collision warning. To optimize the problem, a safe distance model was proposed with considering the driver difference. The three factors of driver′s driving age, driving style and speed were selected as characteristic values, and the response time of the driver was calculated by fuzzy control algorithm. Based on Honda model, a safe distance model considering the driver difference was established. According to the China-new car assessment program（C-NCAP）, the braking condition of the front car was selected to carry out the simulation test for verifying the proposed safe distance model. The results show that the proposed model has good real-time performance and adaptability under the above conditions. The safe distance model not only ensures the driving safety, but also the response time of the driver can reflect the differences of different types of drivers to improve the driving safety.