Abstract: Stroke has become the most common cause of death worldwide. Stroke is the third leading cause of death in the west, after heart disease and cancer, and accounts for 10% of the world’s deaths. The incidence rate of stroke increased exponentially from 40 years old, and the cause of disease was related to age and lifestyle. Prevention, treatment and nursing rehabilitation are the three key aspects of the occurrence and development of stroke.This paper systematically discussed the prevention means and measures of stroke, summarized the treatment strategies of different types of stroke, clarified the nursing and rehabilitation after stroke and prognosis, in order to provide stroke prevention knowledge, treatment strategies and rehabilitation management for nursing staff and the public.