Abstract: In a local comprehensive university, the cultivating mode is generally obsolete, the cultivating mechanism is rigid and the interdisciplinary is lack, these problems have restricted the effect of talent training. In this work, a cultivating mode for training multi-talent agricultural and forestry students by combining research and innovation is present. In order to construct this cultivating mode, it is necessary to strengthen the core competitiveness of agricultural and forestry specialties, to build first-class courses of "the combination of research and innovation", to organize a team of teachers with both major knowledge and engineering practical experience talents, to carry out "whole-course interaction" collaborative education, and to improve the quality assurance system. These measures will provide beneficial reference for the cultivation of outstanding new agricultural science students in local comprehensive university.