Abstract: Spotted seabass（Lateolabrax maculatus） is one of the most important seawater economic fish in China, and its annual output has exceeded 190 000 tons in recent years, which is an important part of the "vegetable basket" project of our daily life. However, due to the lack of effective genetic markers, the breeding technology of spotted seabass is limited, which has become one of the bottlenecks restricting the healthy development of spotted seabass industry in China. In the present study, to explore the association of the single nucleotide polymorphism（SNP） of insulin-like growth factor 3（igf3） gene and the growth traits in spotted seabass, the SNPs characteristics of igf3 gene in spotted seabass population were detected. The results showed that there were four SNP sites on igf3 gene, located at C+2 990T, G+3 037A, C+3 303G, and G+3 602A downstream of the start codon, respectively. The first three SNPs were located in the intron region, and the fourth one was located in the exon region. Although there was no significant correlation between individual SNP and growth traits of spotted seabass（P＞0.05）, the diploids showed significant correlation with grow traits of spotted seabass（P＜0.05）. Among them, the doubled haplotype D2（CCGAGGC） populations showed the greater presentation in four detected growth traits（body weight, head length, body height and body width）, especially significantly higher than that of D3（CTGGCGCC） populations（P＜0.05）. This study provids candidate genes for screening spotted seabass with potential growth advantage, which is benificial for the development of spotted seabass breeding work.