Abstract:
As a green bio-based platform chemical, 2, 5-furan dicarboxylic acid(FDCA) was widely used in polyester, plasticizer, fire protection, medicine, etc. At present, according to the distinction of raw materials for the synthesis of FDCA, the synthetic routes of FDCA could be divided into 5-hydroxymethylfurfural(HMF) route, furoic acid route and other raw material routes. Among them, furfural acid could be prepared from the oxidation of bulk bio-based chemical furfural, and the industrial production of furfural made the preparation of FDCA from furfural acid had the potential advantages of green and economical. Based on this, this paper reviews the research status of four methods for preparing FDCA from furoic acid, including: disproportionation, carbonylation, carboxylation and biocatalysis methods. The paper also summarizes a comparative analysis of the advantages and disadvantages of each method and highlights the progress made in their respective research fields. A comparative analysis indicates that the C-H carboxylation method is a gentle and environmentally friendly process, demonstrating significant potential for large-scale production.