Abstract: This article outline the isolation process, chemical properties and recent progress of levopimaric acid and its derivatives in recent years. The isolation of levopimaric acid mainly depended on the amine reaction, recrystallization and capillary column separation methods. According to the structural characteristics, the pure sample of levopimaric acid could be used to synthesize a wide range of fine chemicals, such as heat conductive material, surface active agent by carboxyl esterification and diene addition, etc. It could be used as a good compound for the selective synthesis of chiral materials with biological activity, too.