Abstract: 2,5-Dimethylfuran (DMF) from renewable biomass is considered as a promising new generation of alternative fuel. DMF has many desirable characteristics and can be directly used in spark ignition (SI) engine or used after mixing with gasoline. The conversion from biomass based platform molecule, 5-hydroxylmethylfurfural (HMF), to DMF has attracted great attention all over the world. Herein, the catalytic reaction mechanisms about the conversion methods from HMF to DMF are elaborated. The state-of-the-art of catalytic conversion approaches for the production of DMF from HMF is systematically summarized and discussed, focusing on noble metal, base metal, synergetic duplex metal catalytic systems.