Abstract: Nowadays, the application of hydrotropes is one of the research hotspots in the field of biorefinery. Hydrotrope can effectively separate the lignocellulosic components to realize the high value-added utilization of the products, such as producting biofuels, biochemicals, and biomaterials. In this work, we provided a review of the applications of hydrotropes for fractination of cellulose, hemicelluloses and lignin, and producting bioethanol, cellulose nanocrystals(CNCs) and nano lignin etc..