Abstract: The traditional resource of squalene is shark liver oil which has not been encouraged to be used. It is very important to search sustainable and safe natural resources, especially plant resources, for squalene preparation, research, and development instead of shark liver oil. The major plant squalene resources including fruits, seeds or oil of olive (Olea europaea L.), Camellia oleifera Abel., amaranth series (Amaranthus tricolor, A. cruentus, A. hypochon-driacus), Terminalia catappa L., Siraitia grosvenorii, Staphylea bumalda, etc., were introduced. Investigation of plant squalene resources could be contributed to the future research and utilization of squalene.