Abstract: Effects of reaction temperature, reaction time, potassium permanganate amount and ratio of acetic acid to water on preparation of pinononic aicd by oxidation of verbenone with potassium permanganate were investigated. The results showed that by keeping the molar ratio of (+)-verbenone to potassium permanganate as 1∶4, reaction temperature 10 ℃, reaction time 2 h and the ratio of acetic acid to water 10∶1, the yield of (+)-pinononic acid reached 77 %. Furthermore, the effect of silica gel as a support on this reaction was also discussed. The results showed that taking silica gel-supported potassium permanganate as oxidant, the yield of the target product could be increased to 81 %.