Abstract: Using black wattle tannin and paraformaldehyde in fluid-wax as organic dispersant, a spherical tannin-chelated resin was prepared through inverse-suspension polymerization. The condition of reaction was determined by means of orthognonal experiment.The optimal condition of synthesis was: m(tannins):m(paraformaldehyde) 12:1, reaction temperature 67℃, reaction time 3.5h, fluid-wax volume 65mL. The structure of the product was characterized by Fourier transform IR, XRD, TG, DSC and SEM. The adsorption mechanism of tannin-chelated resin toward Cr6+ was investigated.