Abstract: Desertification is one of the most severe environmental and social problems. Chemical prevention technology is an important method of desertification control, which is of low-cost, effective and simple for application. In this paper, performance and application of PALS and PMLS, the two kinds of sandy-soil stabilizer, were studied. Both sandy-soil stabilizers were made from lignosulfonate, which is the byproduct of papermaking industry. Through a great deal of performance tests in laboratory, these two stabilizers showed high compressive strength, high resistances against freezing-thawing,aging, wind erosion and water erosion. Results of field application test in Wulanbuhe Desert demonstrate that they are effective on sand stabilization, and their cost are only 70% of anionic polyacrylamide (APAM).