微波辐射下没食子酸异丁酯的合成

SYNTHESIS OF ISO-BUTYL GALLATE UNDER MICROWAVE IRRADIATION

摘要: 采用微波辐射技术,以对甲苯磺酸(PTSA)为催化剂,没食子酸和异丁醇为原料,直接酯化合成没食子酸异丁酯.研究了微波功率、辐射时间、催化剂的用量、酸醇摩尔比等因素对于酯化反应产率的影响,并对产品进行了分析和鉴定.通过正交试验探讨出最佳的反应条件为:没食子酸与异丁醇摩尔比1:17,没食子酸与催化剂摩尔比1:0.05,微波功率510 W(没食子酸用量10.94g),辐射时间60min,平均酯化产率为86.3%.

Abstract: Iso-butyl gallate was synthesized by esterification of gallic acid with iso-butyl alcohol catalyzed by p-toluenesulfonic acid(PTSA) under microwave irradiation. The optimum reaction condition was as follows: molar ratio of gallic acid to iso-butyl alcohol 1:17, molar ratio of gallic acid to catalyst 1:0.05, microwave irradiation power 510 W (gallic acid 10.94 g), for 60 min. Average yield of iso-butyl gallate was 86.3%.