Abstract: Result of experiment shows: the adsorption amount of microcrystalline cellulose MCC for catapol antibiotic is related with catapol’s original concentrationC0. The higher C0 is, the more adsorption of MCC is. The adsorption amount of wood pulp MCC is higher than others. By imitating the physiological condition of human stomach intestine system digestive system, we studied the adsorption and desorption of different kinds of the complex MCC-catapol. The result shows that at pH value 2.0 equivalent to the condition in the stomach of human body, the desorption level arrived the max (63.1% -73.7%); at pH value 9.0 equivalent to the condition in the intestines of human body, the complex which desorbed at pH value 2.0 can still desorb continuously. Total desorption amounts of these two stages reach 70%-90%, which proved that the complex could be used as stomach-intestines medicament.