五指毛桃黄酮和香豆素类成分研究

1. 中国药科大学, 天然药物化学教研室, 江苏, 南京, 210009;2. 暨南大学, 中药及天然药物研究所, 广东, 广州, 510632;3. 广东省中药药效物质基础及创新药物研究重点实验室, 广东, 广州, 510632

详细信息

Studies on Flavonoids and Coumarins in the Roots of Ficus hirta Vahl.

1. Department of Phytochemistry, China Pharmaceutical University, Nanjing 210009, China;2. Institute of Traditional Chinese Medicine & Natural Products, Jinan University, Guangzhou 510632, China;3. Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Guangzhou 510632, China

摘要:
对五指毛桃的化学成分进行了研究.分离得到11个化合物,根据理化性质和波谱数据,分别鉴定为补骨脂素(Ⅰ)、伞形花内酯(Ⅱ)、 5,3',4'-三羟基-3,7-二甲氧基黄酮(Ⅲ)、 5,7,2',4'-四羟基黄酮(Ⅳ)、 5-羟基-3,7,4'-三甲氧基黄酮(Ⅴ)、山柰酚(Ⅵ)、紫云英苷(Ⅶ)、金合欢素 7-O-β-D-吡喃葡萄糖苷(Ⅷ)、木犀草素7-O-β-D-吡喃葡萄糖苷(Ⅸ)、柚皮素(Ⅹ)及胡萝卜苷(Ⅺ).经检索,化合物Ⅱ～Ⅹ为首次从该植物中分离得到,化合物Ⅲ、Ⅳ、Ⅴ、Ⅷ、Ⅸ为首次从该属植物中分离得到.
- 五指毛桃 /
- 化学成分 /
- 黄酮 /
- 香豆素
Abstract:
Chemical constituents in the roots of Ficus hirta Vahl.were studied. Eleven compounds were isolated and their structures were elucidated as psoralen (Ⅰ), umbelliferon(Ⅱ), 5,3',4'-trihydroxy-3,7-dimethoxyflavone(Ⅲ), norartocarpetin(Ⅳ), 5-hydroxy-3,7,4'-trimethoxyflavone(Ⅴ), kaempferol(Ⅵ), astragalin(Ⅶ), acacetin 7-O-β-D-glucopyranoside(Ⅷ), luteolin 7-O-β-D-glucopyranoside(Ⅸ), narigenin(Ⅹ) and daucosterol(Ⅺ), respectively. Compounds Ⅱ-Ⅹ were isolated from this plant for the first time, compounds Ⅲ, Ⅳ, Ⅴ, Ⅷ, Ⅸ were obtained from the genus Ficus for the first time.
- root of Ficus hirta Vahl. /
- chemical constituent /
- flavonoid /
- coumarin