路易斯酸催化莰烯异构酯化合成乙酸异龙脑酯的研究

Synthesis of Isobornyl Acetate from Camphene Isomeric Esterification Catalyzed by Lewis Acids

摘要: 以路易斯酸为催化剂催化莰烯与冰乙酸酯化制备乙酸异龙脑酯，通过催化剂筛选和反应条件的优化，获得了莰烯与冰乙酸酯化反应合成乙酸异龙脑酯的最佳反应条件，即：FeCl3为催化剂，添加量为莰烯质量的10%，反应温度在25℃，反应时间2 h，n（莰烯）：n（冰乙酸）1：3。在此条件下，采用含莰量94.9%的莰烯（莰烯84.8%，三环烯10.1%）为原料进行反应时，莰烯转化率接近99%，乙酸异龙脑酯选择性94%，乙酸异龙脑酯的平均产率88%。

Abstract: Isomeric esterification of camphene with glacial acetic acid catalyzed by Lewis acids was studied to produce isobornyl acetate.And the suitable esterification conditions were examined and optimized as following:FeCl3 as catalyst,catalyst dosage 10%(mass ratio of camphene),reaction temperature 25℃,reaction time 2 h,n(camphene):n(acetic acid)1:3.As results,using 94.9% camphene (the total of camphene 84.8% and tricyclene 10.1%) as raw material,the conversion rate of camphene was nearly 99%,the selectivity of isobornyl acetate reached 94%,and the yield of isobornyl acetate reached more than 88% in the product.