Abstract: In order to reveal the effects of the coupling effect of irrigation, fertilization and aeration on corn yield and root growth, fresh corn "Jingtian 3" was taken as the research object. Irrigation, fertilization and aeration were selected as influencing factors. The corn yield and root dry weight were used as evaluation indexes to conduct a quadratic regression orthogonal rotation test. The test results showed that the order of influence on maize yield was irrigation, aeration, and fertilization; the order of influence on root dry weight was aeration, irrigation, and fertilization. Using Design-Exper10.0 to complete the analysis of variance and significance test on the data, the optimal combination of process parameters was determined: when the irrigation amount was 3600 m~3/hm~2, the fertilization amount was 650 kg/hm~2, the aeration volume was 2 000 m~3/hm~2, and the theoretical corn yield was 9 987 kg/hm~2, dry root weight is 30.25 g. The test results are consistent with the optimization results and meet the requirements of corn agronomic traits.