Abstract: At present, a large amount of livestock and poultry manure produced by animal husbandry has brought great pressure on environmental protection of China. Biogas projects treat manure with anaerobic fermentation, meanwhile generated biogas slurry is difficult to be treated, and it will cause serious pollution to the environment. Aim at this problem,designing a biogas slurry micro-irrigation system by sieves with different mesh filtration, there are all sort of biogas slurry filtering basin, sedimentation basin, sewage pump, irrigation pipeline, filtering tank, water basin, pump, valves, fertilizer applicator, fertilizer tank, emitter and so on. The replacing stainless steel meshes with different diamond and are applied in the preliminarily filtering biogas slurry. The filtering tank composing with 3 different volume（quartz sand, volcanic rocks, sand） is multilevel filtration-purification system. The biogas slurry micro-irrigation system use a special equipment to sluiced the irrigation pipeline, filtering tank and emitter. The system can be set to run two hour with irrigating biogas slurry, and then started the special sluiced equipment. The system running were able to remain in operation without failure or gridlock in three hundred hour. Experimental results show that, more than 79. 5% of suspended solids in biogas slurry can be removed after filtration by different mesh combination of stainless steel mesh,coarse sand, volcanic rock and quartz sand, with 50% of the removal rate of nitrogen,with 10. 5% of the removal rate of phosphorus, with 22.5% of the removal rate of potassium. After some special treatment,the liquid produced by filtration may be used as basically meet the water quality standards for irrigation water. This research study can provide a reference for the treatment and utilization of biogas slurry.