Abstract: Aiming at the problem of low intelligence and low positioning accuracy of plant protection UAV in China, the control system of plant protection UAV based on cloud platform was studied.The plant protection UAV control system was constitute of cloud platform, terminal equipment and plant protection aircraft.The dynamic model of the plant protection aircraft in operation process was calculated, and the control system according to the model was optimized to achieve intelligent and high precision operation of the plant protection UAV,and then ensure the stability of the plant protection aircraft in the flight process.To ensure the effectiveness of the plant protection UAV control system, it is necessary to carry out flight stability and actual flight test.The test results show that the plant protection UAV control system could realize the stability control of UAV.