Abstract: In recent years, with the continuous development and application of agricultural machinery intelligence, farmers have put forward higher requirements for agricultural machinery control functionality, convenience, ease of learning and good experience of human-computer interaction. However, there are a lot of "homogenization" features in various agricultural machinery APP interfaces on the market, which are difficult to meet the requirements of different agricultural machinery in the field. This paper takes "human-machine interaction behavior" as the design goal, based on visual communication technology, and takes the operation interface of cereal combine harvester as the research object to carry out relevant design research.Through analyzing the graphics, text, color and design style of the operation interface of cereal combine harvester, the results show that the optimized operation interface of agricultural machinery can significantly improve the operator’s operation efficiency and working experience, and reduce the operation error rate and fatigue level. The research results can provide a reference process design model for the design of intelligent operation interface of agricultural machinery.